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脊髓性肌萎縮癥蛋白SMA抗體

產品貨號：

BN40312R
中文名稱：

脊髓性肌萎縮癥蛋白SMA抗體
英文名稱：

Rabbit anti-Gemin 2 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40312R-100ul

100ul

￥2360.00

交叉反應：Human,Rat(predicted:Mouse,Pig,Horse,Rabbit) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
BN40312R-200ul

200ul

￥3490.00

交叉反應：Human,Rat(predicted:Mouse,Pig,Horse,Rabbit) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

產品描述

英文名稱	Gemin 2
中文名稱	脊髓性肌萎縮癥蛋白SMA抗體
別名	SMA; Gemin2; Component of gems 2; Gem (nuclear organelle) associated protein 2; Gem associated protein 2; GEMI2_HUMAN; Gemin-2; gemin2; SIP 1; SIP-1; SIP1; SIP1 delta; SIP1-delta ; SMN interacting protein 1; SMN interacting protein 1 delta; SMN-interacting protein 1; Survival interacting protein 1; Survival of motor neuron protein interacting protein 1; Survival of motor neuron protein-interacting protein 1.
研究領域	細胞生物神經生物學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Rat, (predicted: Mouse, Pig, Horse, Rabbit, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	32kDa
細胞定位	細胞核細胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Gemin 2:101-200/280
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]. Function: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. Subunit: Part of the core SMN complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP. Interacts directly with GEMIN5. Subcellular Location: Nucleus, gem. Cytoplasm. Note=Localized in subnuclear structures next to coiled bodies, called gems, which are highly enriched in spliceosomal snRNPs. Also found in the cytoplasm. Similarity: Belongs to the gemin-2 family. SWISS: O14893 Gene ID: 8487 Database links: Entrez Gene: 8487 Human Entrez Gene: 66603 Mouse Entrez Gene: 84404 Rat Omim: 602595 Human SwissProt: O14893 Human SwissProt: Q9CQQ4 Mouse SwissProt: Q9QZP1 Rat Unigene: 652307 Human Unigene: 35353 Mouse Unigene: 34143 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.