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    希佩爾-林道結合蛋白抗體
    • 產品貨號:
      BN40381R
    • 中文名稱:
      希佩爾-林道結合蛋白抗體
    • 英文名稱:
      Rabbit anti-PFDN3 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN40381R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse 推薦應用:WB,IHC-P,IHC-F,ICC,IF

    • BN40381R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse 推薦應用:WB,IHC-P,IHC-F,ICC,IF

    產品描述

    英文名稱PFDN3
    中文名稱希佩爾-林道結合蛋白抗體
    別    名HIBBJ 46; HIBBJ46; PFD 3; PFD3; PFD3_HUMAN; PFDN 3; Prefoldin 3; Prefoldin subunit 3; Prefoldin3; VBP 1; VBP-1; VBP1; VHL binding protein 1; VHL-binding protein 1; Von Hippel Lindau binding protein 1; Von Hippel-Lindau-binding protein 1.  
    研究領域細胞生物  信號轉導  轉錄調節因子  結合蛋白  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, 
    產品應用WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量23kDa
    細胞定位細胞核 細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human PFDN3:51-150/197 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Jan 2015]

    Function:
    Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

    Subcellular Location:
    Cytoplasm. Nucleus. In complex with VHL can translocate to the nucleus.

    Tissue Specificity:
    Ubiquitous.

    Similarity:
    Belongs to the prefoldin subunit alpha family.

    SWISS:
    P61758

    Gene ID:
    7411

    Database links:

    Entrez Gene: 508727 Cow

    Entrez Gene: 481089 Dog

    Entrez Gene: 7411 Human

    Entrez Gene: 22327 Mouse

    Omim: 300133 Human

    SwissProt: Q2TBX2 Cow

    SwissProt: P61758 Human

    SwissProt: P61759 Mouse

    Unigene: 436803 Human

    Unigene: 8294 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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