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    首頁>>免疫學(xué)>>一抗>>MED18蛋白抗體
    MED18蛋白抗體
    • 產(chǎn)品貨號:
      BN40536R
    • 中文名稱:
      MED18蛋白抗體
    • 英文名稱:
      Rabbit anti-MED18 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產(chǎn)品規(guī)格

      售價(jià)

      備注

    • BN40536R-100ul

      100ul

      ¥2360.00

      交叉反應(yīng):Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep,Rhesus monkey, Gorilla, Catfish, Orangutan, Platypus) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF

    • BN40536R-200ul

      200ul

      ¥3490.00

      交叉反應(yīng):Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep,Rhesus monkey, Gorilla, Catfish, Orangutan, Platypus) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF

    產(chǎn)品描述

    英文名稱MED18
    中文名稱MED18蛋白抗體
    別    名FLJ20045; hMED 18; hMED18; Human Mediator of RNA Polymerase II Transcription; MED 18; med18; MED18_HUMAN; Mediator complex subunit 18; Mediator of RNA polymerase II transcription subunit 18; Mediator of RNA polymerase II transcription subunit 18 homolog; OTTHUMP00000003645; p28b; TRAP/mediator complex subunit p28b.  
    研究領(lǐng)域轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀遺傳學(xué)  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, Rhesus monkey, Gorilla, Catfish, Orangutan, Platypus)
    產(chǎn)品應(yīng)用IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量24kDa
    細(xì)胞定位細(xì)胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human MED18:31-130/208 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]

    Function:
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

    Subcellular Location:
    Nucleus.

    Similarity:
    Belongs to the Mediator complex subunit 18 family.

    SWISS:
    Q9BUE0

    Gene ID:
    54797

    Database links:

    Entrez Gene: 540695 Cow

    Entrez Gene: 54797 Human

    Entrez Gene: 67219 Mouse

    Entrez Gene: 393306 Zebrafish

    Omim: 612384 Human

    SwissProt: Q0VCD4 Cow

    SwissProt: Q9BUE0 Human

    SwissProt: Q9CZ82 Mouse

    Unigene: 479911 Human

    Unigene: 45929 Mouse

    Unigene: 19506 Zebrafish



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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