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血管內(nèi)皮生長(zhǎng)因子C型抗體

產(chǎn)品貨號(hào)：

BN40639R
中文名稱：

血管內(nèi)皮生長(zhǎng)因子C型抗體
英文名稱：

Rabbit anti-VEGF-C Polyclonal antibody
品牌：

Biorigin

貨號(hào)

產(chǎn)品規(guī)格

售價(jià)

備注
BN40639R-100ul

100ul

￥2360.00

交叉反應(yīng)：Human,Mouse(predicted:Rat,Pig,Horse) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
BN40639R-200ul

200ul

￥3490.00

交叉反應(yīng)：Human,Mouse(predicted:Rat,Pig,Horse) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱	VEGF-C
中文名稱	血管內(nèi)皮生長(zhǎng)因子C型抗體
別名	Vascuoar endothelial growth factor-C; AW228853; Flt4 ligand; Flt4-L; VEGF2; VEGFC; VRP; VEGFC_HUMAN.
研究領(lǐng)域	細(xì)胞生物血管內(nèi)皮細(xì)胞
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Mouse, (predicted: Rat, Pig, Horse, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	13/46kDa
細(xì)胞定位	分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human VEGF-C:112-170/419
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	Vascular endothelial growth factors (VEGFs), also known as vasculotropins, are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. The target cell specificity of VEGF is restricted to vascular endothelial cells. Vascular Endothelial Growth Factor C (VEGFC) is a member of the VEGF subfamily of PDGF-related growth factors. It is the ligand for Flt4 (VEGFR3) and KDR (VEGFR2). VEGFC binds Flt4 and induces tyrosine autophosphorylation of VEGFR3 and VEGFR2. VEGFC also stimulates the migration of bovine capillary endothelial cells in collagen gel. It is a specific growth factor for the lymphatic vascular system and mediates lymphangiogenesis. VEGFC is abundantly expressed in heart and skeletal muscle. Other tissues such as lung and kidney also express VEGFC. Subunit: Homodimer; non-covalent and antiparallel. Subcellular Location: Secreted. Tissue Specificity: Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. Similarity: Belongs to the PDGF/VEGF growth factor family. SWISS: P49767 Gene ID: 7424 Database links: Entrez Gene: 7424 Human Entrez Gene: 22341 Mouse Entrez Gene: 114111 Rat Omim: 601528 Human SwissProt: P49767 Human SwissProt: P97953 Mouse SwissProt: O35757 Rat Unigene: 435215 Human Unigene: 1402 Mouse Unigene: 6913 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.