貨號
產品規格
售價
備注
BN40731R-100ul
100ul
￥2360.00
交叉反應：Mouse,Rat 推薦應用：WB
BN40731R-200ul
200ul
￥3490.00
交叉反應：Mouse,Rat 推薦應用：WB
產品描述
| 英文名稱 | MRas |
| 中文名稱 | 原癌基因M-ras抗體 |
| 別 名 | M-RAS; M ras; muscle RAS oncogene homolog precursor; Muscle and microspikes Ras; Muscle Ras oncogene homologue; R ras3; R-ras3; Ras related protein MRas; Ras related protein RRas3; RRas3; XRas. |
| 研究領域 | 腫瘤 細胞生物 免疫學 細胞凋亡 轉錄調節因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Mouse, Rat, |
| 產品應用 | WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 23kDa |
| 細胞定位 | 細胞漿 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse MRas:201-259/259 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產品介紹 | MRas is a member of the RAS superfamily of GTP-binding proteins which are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRas participates in reorganisation of actin cytoskeleton. It is also involved in focal adhesion and can activate MAPK signalling. Function: May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Tissue Specificity: Expression highly restricted to the brain and heart. Similarity: Belongs to the small GTPase superfamily. Ras family. SWISS: O08989 Gene ID: 17532 Database links: Entrez Gene: 22808 Human Entrez Gene: 17532 Mouse Omim: 608435 Human SwissProt: O14807 Human SwissProt: O08989 Mouse Unigene: 527021 Human Unigene: 2045 Mouse Unigene: 10641 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. M-ras癌變基因的表達產物Ras蛋白存在于多數腫瘤之中，目前是腫瘤研究較重要的蛋白之一. |
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