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熱休克蛋白B2抗體

產品貨號：

BN41017R
中文名稱：

熱休克蛋白B2抗體
英文名稱：

Rabbit anti-HSPB2 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41017R-100ul

100ul

￥2360.00

交叉反應：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
BN41017R-200ul

200ul

￥3490.00

交叉反應：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

產品描述

英文名稱	HSPB2
中文名稱	熱休克蛋白B2抗體
別名	DMPK-binding protein; Heat shock 27kD protein 2; Heat shock 27kDa protein 2; Heat shock protein beta-2; Heat-shock protein beta-2; Hs.78846; HSP27; HspB2; HSPB2_HUMAN; LOH11CR1K; MGC133245; MKBP.
研究領域	腫瘤細胞生物免疫學信號轉導
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	20kDa
細胞定位	細胞核細胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human HSPB2:101-182/182
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB2 (heat shock 27 kDa protein 2), also known as HSP 27 or MKBP, is a 182 amino acid protein that belongs to the heat shock protein family and is expressed preferentially in heart and skeletal muscle. Localized to mitochondria, HSPB2 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also interact with the Actin cytoskeleton and prevent apoptotic cell death. HSPB2 is abundantly expressed in several cancer cell lines, suggesting that HSPB2 may be an important factor in tumor transformation and metastasis. Function: May regulate the kinase DMPK. Subunit: Interacts with DMPK; may enhance its kinase activity. Subcellular Location: Cytoplasm. Nucleus. Localizes to nuclear foci. Tissue Specificity: Expressed preferentially in skeletal muscle and heart. Similarity: Belongs to the small heat shock protein (HSP20) family. SWISS: Q16082 Gene ID: 3316 Database links: Entrez Gene: 3316 Human Entrez Gene: 69253 Mouse Entrez Gene: 161476 Rat Omim: 602179 Human SwissProt: Q16082 Human SwissProt: Q99PR8 Mouse SwissProt: O35878 Rat Unigene: 709660 Human Unigene: 1980 Mouse Unigene: 22486 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.