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    首頁>>免疫學>>一抗>>N-鈣粘附分子抗體
    N-鈣粘附分子抗體
    • 產品貨號:
      BN41119R
    • 中文名稱:
      N-鈣粘附分子抗體
    • 英文名稱:
      Rabbit anti-N-Cadherin Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41119R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse(predicted:Rat) 推薦應用:WB,ELISA

    • BN41119R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse(predicted:Rat) 推薦應用:WB,ELISA

    產品描述

    英文名稱N-Cadherin
    中文名稱N-鈣粘附分子抗體
    別    名Cadherin 2; Cadherin 2 N cadherin neuronal; Cadherin 2 type 1; Cadherin 2 type 1 N cadherin neuronal; cadherin 2 type 1 N-cadherin neuronal; Cadherin2; Calcium dependent adhesion protein neuronal; CD325; CD325 antigen; CDH2; CDHN; CDw325; CDw325 antigen; N cadherin 1; NCAD; Neural Cadherin; Neural Cadherin.  
    研究領域腫瘤  細胞生物  免疫學  激酶和磷酸酶  細胞粘附分子  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, )
    產品應用WB=1:500-1000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量97/99kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human N-Cadherin:750-850-905 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMedPubMed
    產品介紹This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

    Function:
    Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.

    Subcellular Location:
    Cell membrane.

    Similarity:
    Contains 5 cadherin domains.

    SWISS:
    P19022

    Gene ID:
    1000

    Database links:

    Entrez Gene: 1000 Human

    Entrez Gene: 281062 Cow

    Entrez Gene: 12558 Mouse

    Entrez Gene: 83501 Rat

    Omim: 114020 Human

    SwissProt: P19022 Human

    SwissProt: P15116 Mouse

    SwissProt: Q9Z1Y3 Rat

    Unigene: 464829 Human

    Unigene: 606106 Human

    Unigene: 257437 Mouse

    Unigene: 23200 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    細胞粘附蛋白(Call Adhesion Protein) N-鈣粘附分子屬于依賴鈣離子的細胞間糖蛋白粘附分子的一部分,主要是參與細胞間同源性粘附,調控和介導細胞間相互反應。


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