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    首頁>>免疫學>>一抗>>減數分裂核分裂蛋白1/GAJ抗體
    減數分裂核分裂蛋白1/GAJ抗體
    • 產品貨號:
      BN41276R
    • 中文名稱:
      減數分裂核分裂蛋白1/GAJ抗體
    • 英文名稱:
      Rabbit anti-MND1 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41276R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse(predicted:Rat) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41276R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse(predicted:Rat) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱MND1
    中文名稱減數分裂核分裂蛋白1/GAJ抗體
    別    名GAJ protein; Homolog of yeast MND1; Meiotic nuclear division 1, S. cerevisiae. homolog of antibody; Meiotic nuclear division protein 1 homolog; Meiotic nuclear divisions 1 homolog (S. cerevisiae); Meiotic nuclear divisions 1 homolog; MGC134110; MND1; RGD1309007; 2610034E18Rik; AI591601.  
    研究領域細胞生物  細胞周期蛋白  細胞分化  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量24kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human GAJ/MND1:1-100/205 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹The product of the GAJ gene associates with HOP2 to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 and DMC1. Both the MND1 and HOP2 genes are indispensable for meiotic recombination.

    Function:
    Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis (By similarity). Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.

    Subunit:
    Heterodimer with PSMC3IP/HOP2. MND1-PSMC3IP interacts with DMC1 and RAD51 and binds preferentially to dsDNA.

    Subcellular Location:
    Nucleus (Probable)

    Similarity:
    Belongs to the MND1 family.

    SWISS:
    Q9BWT6

    Gene ID:
    84057

    Database links:

    Entrez Gene: 84057 Human

    Omim: 611422 Human

    SwissProt: Q9BWT6 Human

    Unigene: 294088 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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