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BN41476R-50ul
50ul
￥1486.00
交叉反應(yīng)：Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41476R-100ul
100ul
￥2360.00
交叉反應(yīng)：Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41476R-200ul
200ul
￥3490.00
交叉反應(yīng)：Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
產(chǎn)品描述
| 英文名稱 | Calretinin |
| 中文名稱 | 鈣結(jié)合蛋白抗體 |
| 別 名 | 29 kDa calbindin; CAB 29; CAB29; CAL 2; CAL2; CALB 2; CALB2; Calbindin 2 29kDa; Calbindin 2; Calbindin D29K; Calbindin2; CR; CALB2_HUMAN; Calretinin. |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 結(jié)合蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 29kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Calretinin:211-271/271 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | Calretinin is a calcium-binding protein which is abundant in auditory neurons. It belongs to the calbindin family. Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin1. Function: Calretinin is a calcium-binding protein which is abundant in auditory neurons. Tissue Specificity: Brain. Similarity: Belongs to the calbindin family. Contains 6 EF-hand domains. SWISS: P22676 Gene ID: 794 Database links: Entrez Gene: 396255 Chicken Entrez Gene: 794 Human Entrez Gene: 12308 Mouse Entrez Gene: 393684 Zebrafish Omim: 114051 Human SwissProt: P07090 Chicken SwissProt: P22676 Human SwissProt: Q08331 Mouse Unigene: 106857 Human Unigene: 2755 Mouse Unigene: 10321 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 鈣結(jié)合蛋白(Calretinin,CR)主要存在于神經(jīng)組織中，近10%的腺癌可以表達(dá)此蛋白的局部染色陽性，而絕大多數(shù)的間皮瘤為陽性表達(dá)，因此它是診斷間皮瘤的一個(gè)有用的標(biāo)記物 。 鈣結(jié)合蛋白是平滑肌和非肌性調(diào)控蛋白。它可以與肌動(dòng)蛋白、肌球蛋白、原肌球蛋白和鈣調(diào)素相互作用。 |
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