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    首頁>>免疫學>>一抗>>鈣結合蛋白抗體
    鈣結合蛋白抗體
    • 產品貨號:
      BN41476R
    • 中文名稱:
      鈣結合蛋白抗體
    • 英文名稱:
      Rabbit anti-Calretinin Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41476R-50ul

      50ul

      ¥1486.00

      交叉反應:Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    • BN41476R-100ul

      100ul

      ¥2360.00

      交叉反應:Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    • BN41476R-200ul

      200ul

      ¥3490.00

      交叉反應:Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    產品描述

    英文名稱Calretinin
    中文名稱鈣結合蛋白抗體
    別    名29 kDa calbindin; CAB 29; CAB29; CAL 2; CAL2; CALB 2; CALB2; Calbindin 2 29kDa; Calbindin 2; Calbindin D29K; Calbindin2; CR; CALB2_HUMAN; Calretinin.  
    研究領域神經生物學  結合蛋白  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量29kDa
    細胞定位細胞漿 細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Calretinin:211-271/271 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Calretinin is a calcium-binding protein which is abundant in auditory neurons. It belongs to the calbindin family. Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin1.

    Function:
    Calretinin is a calcium-binding protein which is abundant in auditory neurons.

    Tissue Specificity:
    Brain.

    Similarity:
    Belongs to the calbindin family.
    Contains 6 EF-hand domains.

    SWISS:
    P22676

    Gene ID:
    794

    Database links:

    Entrez Gene: 396255 Chicken

    Entrez Gene: 794 Human

    Entrez Gene: 12308 Mouse

    Entrez Gene: 117059 Rat

    Entrez Gene: 393684 Zebrafish

    Omim: 114051 Human

    SwissProt: P07090 Chicken

    SwissProt: P22676 Human

    SwissProt: Q08331 Mouse

    SwissProt: P47728 Rat

    Unigene: 106857 Human

    Unigene: 2755 Mouse

    Unigene: 10321 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


    鈣結合蛋白(Calretinin,CR)主要存在于神經組織中,近10%的腺癌可以表達此蛋白的局部染色陽性,而絕大多數的間皮瘤為陽性表達,因此它是診斷間皮瘤的一個有用的標記物 。
    鈣結合蛋白是平滑肌和非肌性調控蛋白。它可以與肌動蛋白、肌球蛋白、原肌球蛋白和鈣調素相互作用。


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