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    首頁>>免疫學>>一抗>>骨鈣蛋白/骨鈣素抗體
    骨鈣蛋白/骨鈣素抗體
    • 產品貨號:
      BN41538R
    • 中文名稱:
      骨鈣蛋白/骨鈣素抗體
    • 英文名稱:
      Rabbit anti-Osteocalcin Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41538R-50ul

      50ul

      ¥1486.00

      交叉反應:Human,Mouse(predicted:Rat,Dog,Cow,Horse) 推薦應用:IHC-P,IHC-F,IF,ELISA

    • BN41538R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse(predicted:Rat,Dog,Cow,Horse) 推薦應用:IHC-P,IHC-F,IF,ELISA

    • BN41538R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse(predicted:Rat,Dog,Cow,Horse) 推薦應用:IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱Osteocalcin
    中文名稱骨鈣蛋白/骨鈣素抗體
    別    名Osteocalcin Propeptide; Osteocalcin; Osteocalcin precursor; Gamma-carboxyglutamic acid-containing protein; Bone Gla-protein; BGLAP; Bone gamma carboxyglutamate protein; BGLAP; BGP; Bone gamma carboxyglutamate gla protein osteocalcin; Bone gamma carboxyglutamate protein; Bone Gla protein; Gamma carboxyglutamic acid containing protein; OC; PMF1; OSTCN_HUMAN.  



    研究領域免疫學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, Dog, Cow, Horse, )
    產品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量11kDa
    細胞定位分泌型蛋白 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human BGP:21-80/100 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite.

    Function:
    Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.

    Subcellular Location:
    Secreted.

    Post-translational modifications:
    Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.

    Similarity:
    Belongs to the osteocalcin/matrix Gla protein family.
    Contains 1 Gla (gamma-carboxy-glutamate) domain.

    SWISS:
    P02818

    Gene ID:
    632

    Database links:

    Entrez Gene: 281646 Cow

    Entrez Gene: 632 Human

    Entrez Gene: 397530 Pig

    Entrez Gene: 25295 Rat

    Omim: 112260 Human

    SwissProt: P02820 Cow

    SwissProt: P02818 Human

    SwissProt: Q8HYY9 Pig

    SwissProt: P04640 Rat

    Unigene: 654541 Human

    Unigene: 9722 Rat




    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    骨鈣素又稱骨γ-羧谷氨酸包含蛋白


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