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β-酪蛋白抗體

產(chǎn)品貨號：

BN41610R
中文名稱：

β-酪蛋白抗體
英文名稱：

Rabbit anti-Beta-casein Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價

備注
BN41610R-50ul

50ul

￥1486.00

交叉反應(yīng)：Human,Cow,Goat(predicted:Sheep) 推薦應(yīng)用：WB,ELISA
BN41610R-100ul

100ul

￥2360.00

交叉反應(yīng)：Human,Cow,Goat(predicted:Sheep) 推薦應(yīng)用：WB,ELISA
BN41610R-200ul

200ul

￥3490.00

交叉反應(yīng)：Human,Cow,Goat(predicted:Sheep) 推薦應(yīng)用：WB,ELISA

產(chǎn)品描述

英文名稱	Beta-casein
中文名稱	β-酪蛋白抗體
別名	Beta-casein; Casoparan; Antioxidant peptide; Casohypotensin; CASB; CASB_BOVIN; Casein beta; CSN 2; Csn2; CASB_BOVIN.

研究領(lǐng)域	細胞生物免疫學(xué)
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Cow, Goat, (predicted: Sheep, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	24kDa
細胞定位	分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from cow Beta-casein:16-100/224
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	Milk proteins are crucial for the development of all newborn mammals and caseins constitute the major proteins in mammalian milk. b- and k-caseins are the only caseins present in human milk. The b-casein/k-casein ratio is higher in colostrum than in transitional and mature milk and is related to a better digestibility of colostrum casein micelles by the neonate during the first days of life. Human b-casein-encoding gene (Bca) contains a highly phosphorylated site, which is responsible for the calcium-binding capacity of b-casein. A common set of transcription factors are required for the expression of b-casein. Multiple binding sites for Stat5, C/EBPb (CCAAT/enchancer-binding protein) and several half-sites for glucocorticoid receptor (GR) are identified in the distal human enhancer of the b-casein gene. b-casein gene transcription is regulated primarily by a composite response element (CoRE), which integrates signaling from the lactogenic hormones PRL, insulin and hydrocortisone in mammary epithelial cells. NFkB functions as a negative regulator of b-casein gene expression during pregnancy by interfering with Stat5 tyrosine phosphorylation Function: Important role in determination of the surface properties of the casein micelles. Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It also acts as a bradykinin-potentiating peptide. Casohypotensin acts as a bradykinin-potentiating peptide. Induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A. Antioxidant peptide has antioxidant activity. Subcellular Location: Secreted. Tissue Specificity: Mammary gland specific. Secreted in milk. Similarity: Belongs to the beta-casein family. SWISS: P11839 Gene ID: 443391 Database links: Entrez Gene: 1447 Human Entrez Gene: 281099 Bovin Entrez Gene: 443391 Sheep Omim: 115460 Human SwissProt: P05814 Human SwissProt: P02666 Bovin Unigene: 2242 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.