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β1-6 N-乙酰氨基葡萄糖轉移酶2抗體

產品貨號：

BN41688R
中文名稱：

β1-6 N-乙酰氨基葡萄糖轉移酶2抗體
英文名稱：

Rabbit anti-GCNT2 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41688R-50ul

50ul

￥1486.00

交叉反應：Human,Mouse,Rat(predicted:Horse) 推薦應用：WB,ELISA
BN41688R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse,Rat(predicted:Horse) 推薦應用：WB,ELISA
BN41688R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse,Rat(predicted:Horse) 推薦應用：WB,ELISA

產品描述

英文名稱	GCNT2
中文名稱	β1-6 N-乙酰氨基葡萄糖轉移酶2抗體
別名	bA360O19.2; bA421M1.1; Beta 1 6 N acetylglucosaminyltransferase 2; CCAT; GCNT 2; GCNT2C; GCNT5; Glucosaminyl (N acetyl) transferase 2 I branching enzyme (I blood group); Glucosaminyl (N acetyl) transferase 2 I branching enzyme; I beta 1 6 N acetylglucosaminyltransferase; I branching beta 1 6 acetylglucosaminyltransferase; I branching enzyme; IGNT; II; Ii blood group; MGC163396; N acetylglucosaminyltransferase; N acetyllactosaminide beta 1 6 N acetylglucosaminyltransferase; NACGT1; NAGCT1; ULG3.
研究領域	腫瘤細胞生物信號轉導干細胞
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, (predicted: Rat, Horse, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	46kDa
細胞定位	細胞漿細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human GCNT2:151-250/400
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	Belonging to the glycosyltransferase 14 family, GCNT2 (glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)), also known as II, N-acetylglucosaminyltransferase, IGNT, CCAT, ULG3, GCNT5, GCNT2C or NACGT1, is a 400 amino acid glycosyltransferase that localizes to the Golgi apparatus. Other members of the glycosyltransferase 14 family include GCNT1, GCNT3, GCNT4, GCNT6 and GCNT7. A single-pass type II membrane protein, GCNT2 functions as a branching enzyme known as beta-1,6-N-acetylglucosaminyltransferase, which converts fetal i antigen to adult I antigen in erythrocytes during embryonic development. With expression levels increasing significantly during oncogenesis and development, GCNT2 is found at highest levels in adult prostate and fetal brain, and is found at low levels in heart, small intestine, colon, brain, pancreas and kidney. Function: GCNT2 is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase that converts linear into branched poly-N-acetyllactosaminoglycans and is responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding 3 different isoforms have been described. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: In the adult, highly expressed in prostate and to a lesser extent in small intestine and colon. Barely detected in heart, brain, kidney and pancreas. No expression in placenta, lung, liver, skeletal muscle, spleen, thymus, testis, ovary and peripheral blood leukocytes. In fetus, highly expressed in brain and to a lesser extent in lung and kidney. Barely detected in liver. Similarity: Belongs to the glycosyltransferase 14 family. SWISS: Q8N0V5 Gene ID: 2651 Database links: Entrez Gene: 2651 Human Entrez Gene: 14538 Mouse Omim: 600429 Human SwissProt: Q8N0V5 Human SwissProt: P97402 Mouse Unigene: 519884 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.