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    首頁>>免疫學>>一抗>>S腺苷L-同型半胱氨酸水解酶抗體
    S腺苷L-同型半胱氨酸水解酶抗體
    • 產品貨號:
      BN41919R
    • 中文名稱:
      S腺苷L-同型半胱氨酸水解酶抗體
    • 英文名稱:
      Rabbit anti-SAHH Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41919R-50ul

      50ul

      ¥1486.00

      交叉反應:Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    • BN41919R-100ul

      100ul

      ¥2360.00

      交叉反應:Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    • BN41919R-200ul

      200ul

      ¥3490.00

      交叉反應:Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    產品描述

    英文名稱SAHH
    中文名稱S腺苷L-同型半胱氨酸水解酶抗體
    別    名Adenosylhomocysteinase; AdoHcyase; ahcY; S adenosyl L homocysteine hydrolase; S adenosylhomocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase; SAHH; SAHH_HUMAN.  


    研究領域腫瘤  細胞生物  免疫學  信號轉導  轉錄調節因子  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量48kDa
    細胞定位細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human SAHH:25-125/432 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

    Function:
    Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

    Subunit:
    Homotetramer.

    Subcellular Location:
    Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

    DISEASE:
    Defects in AHCY are the cause of hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) [MIM:613752]. A metabolic disorder characterized by hypermethioninemia associated with failure to thrive, mental and motor retardation, facial dysmorphism with abnormal hair and teeth, and myocardiopathy.

    Similarity:
    Belongs to the adenosylhomocysteinase family.

    SWISS:
    P23526

    Gene ID:
    191

    Database links:

    Entrez Gene: 191 Human

    Entrez Gene: 269378 Mouse

    Entrez Gene: 29443 Rat

    Omim: 180960 Human

    SwissProt: P23526 Human

    SwissProt: P50247 Mouse

    SwissProt: P10760 Rat

    Unigene: 388004 Human

    Unigene: 330692 Mouse

    Unigene: 371964 Mouse

    Unigene: 5878 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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